On GnuPG 2.4.8 (gpg4win 4.4.1, Windows 11), attempting to configure gpg-agent to use the --enable-win32-openssh-support option can seemingly only be done by manually editing gpg-agent.conf.
- gpgconf --list-options gpg-agent does not report any output line containing enable-win32-openssh-support, even if gpg-agent.conf contains only that line.
- echo enable-win32-openssh-support:0:1 | gpgconf --change-options gpg-agent fails with the error message unknown option enable-win32-openssh-support.
Given these symptoms, I would assume that when the command-line option was added, the corresponding configuration option for gpgconf was forgotten.