Forgot to mention one thing: after changing my user folder directory I lost all my Outlook contacts. I was able to recover them... make sure you have a backup before attempting this!

I just had the same issue as hurui200320. My user name contains a "ç" and Kleopatra did not start. The Windows event logger reported a crash in libstdc++-6.dll. This was with gpg4win-3.1.16. Installing gnupg 2.3.1 did not change anything.