Similar to the warning, that Windows XP is unsupported during the installation of gpg4win, there should be a message that Windows Vista is unsupported as well.
On a side note: We should describe a workaround as a release note how to work with gpg4win with no qt-applications at all (refer to another pinentry and use gpa instead of kleopatra - maybe this could be integrated in the installation progress for Version 3.x)