It has been reported in T3814 and now again by another Gpg4win user. Fresh install, they try to generate a key and it fails with general error, where the underlying cause is a trustdb corruption.
Here is such a trustdb:
Werner do you have any idea how this can happen or advice how to further debug this? I don't see a 0d0a in the file so I don't think its a textmode problem this time ;-)