If you en-/decrypt the notepad using S/MIME for yourself and for others and then change the protocol to OpenPGP, you will get an error "No matching certificates or groups found" for the "encrypt to others" line:
The same if you do the switch from S/MIME to OpenPGP.
Looks like in the "encrypt to me" line the pre-selected certificates are changed, but not in the "encrypt to others" line.